About Apheris
At Apheris, we are building the future of how AI is applied in pharmaceutical R&D.
We enable leading pharmaceutical teams to discover and develop drugs faster. We host the industry’s largest federated data networks for drug discovery AI, spanning co-folding, ADMET, and antibody developability.
Across these networks, models are trained on proprietary industry datasets to achieve higher performance and broader applicability while keeping data control and IP protected. We deliver these superior models through drug discovery applications that enable teams to run them at scale, further customize them, and integrate them into existing R&D workflows.
- AI Structural Biology (AISB) Network: Eight top-20 pharma companies collaborate in the field of co-folding, structure-based binding affinity predictions and antibody design.
- ADMET Network: Five top-50 pharma and biotechs collaborate to improve small-molecule property prediction and expand to further drug modalities (e.g., PROTACs).
- Antibody Developability Network: Pharma partners collaborate to federate historical and purpose-built antibody developability datasets for secure ML training, without data leaving each partner’s environment.
About the role
We are hiring a Technical Chief of Staff to the CTO to act as a force multiplier for our technical and product organization. This is a hands-on, execution-focused role at the center of product development, customer engagement, and cross-functional delivery. You will work directly with the CTO to ensure technical priorities translate into high-quality customer outcomes, clear internal execution, and reduced iteration overhead.
You will serve as the CTO’s proxy across customer preparation, technical follow-ups, and internal coordination. You will operate with significant autonomy and discretion from day one. You will be expected to anticipate issues, surface trade-offs, and keep the organization focused and moving at pace. This role is designed for someone with a strong technical foundation who thrives in fast-paced environments, enjoys turning ambiguity into concrete outputs, and is comfortable operating in front of customers.
What you will do
- Enable technical leadership and execution
- Act as a force multiplier for the CTO by translating priorities and expectations into concrete actions, deliverables, and timelines.
- Reduce iteration overhead by working with owners across engineering and product teams to clarify next steps, raise quality, and ensure outputs meet expectations before CTO review.
- Proactively identify where work is getting stuck and drive progress through structured proposals, clear scoping, and follow-through.
- Customer preparation and engagement
- Own preparation for technical customer meetings, including:
- Understanding end-to-end technical stacks and (machine learning) workflows.
- Creating clear, compelling customer-facing narratives and presentations.
- Coordinating inputs across teams.
- Ensure strong follow-ups after customer meetings:
- Coordinate internal ownership and track execution.
- Prepare materials and agendas for subsequent sessions.
- As soon as possible: be able to run technical customer meetings, bringing in subject-matter experts as needed and ensuring high-quality outcomes.
- Drive cross-functional outcomes
- Keep cross-functional product and engineering initiatives moving by:
- Clarifying goals and expected outputs.
- Helping owners break down complex tasks into actionable steps.
- Proposing initial drafts (e.g., architecture diagrams, workflows, or outlines) to accelerate feedback and decision-making.
- Support process improvements that increase execution speed and clarity, while respecting clear ownership boundaries.
- Drive technical scoping and enhance product communication across teams
- Enable teams through shared frameworks, templates, and best practices to improve alignment, speed, and quality across technical and product work.
- Contribute to customer-facing materials, proposals, and internal documents to raise overall quality.
- Translate high-level feedback into concrete improvements in preparation, narrative, and execution.
- Strategic and ad-hoc initiatives
- Support early scoping of new opportunities or special projects by
- Structuring initial workflows and technical approaches.
- Coordinating early inputs from product, engineering, and computational drug discovery.
You will operate as an execution partner and force-multiplier, ensuring the right things happen quickly and to a high standard.
